理查德·奎斯:新冠肺炎康复后,我以为自己是安全的。现在我的抗体正在减弱

2020-10-14 17:30

Richard Quest: After recovering from Covid-19, I thought I was safe. Now my antibodies are waning Pzd世界播

理查德·奎斯:新冠肺炎康复后,我以为自己是安全的。现在我的抗体正在减弱Pzd世界播


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Richard Quest reveals positive coronavirus test during his show (April 2020) Pzd世界播

理查德·奎斯特在他的节目中发现冠状病毒检测呈阳性(2020年4月)Pzd世界播


I recovered from Covid-19 back in April. I was fortunate: My symptoms, while nasty, were minor compared to others. I had the hacking dry cough and I was fatigued to the point where I would spend many hours on the sofa. But I never had breathing difficulties, nor required hospital treatment. Pzd世界播

早在4月份,我就从新冠肺炎那里康复了。我很幸运:我的症状虽然很严重,但与其他人相比微不足道。我干咳得厉害,疲倦到要在沙发上呆上好几个小时的地步。但我从来没有呼吸困难,也不需要住院治疗。Pzd世界播


Whenever the question of catching it again has come up since, I airily and hubristically said, "Oh, I've had it, and have antibodies to prove it." At least I did until Friday, when my third antibody test came back negative. Pzd世界播

从那以后,每当有人问我要不要再染上它时,我就轻快而傲慢地说:“哦,我得了,而且有抗体可以证明。”至少在周五之前我是这样做的,当时我的第三次抗体检测结果为阴性。Pzd世界播


I was in shock. Even though it's not clear antibodies do actually offer immunity, I had treated my previous AB positive tests as a shield I could wave, crying, "Been there. Done that. I'm OK." Rightly or wrongly. Now my precious protection had vanished. Pzd世界播

我吓坏了。尽管目前还不清楚抗体是否真的能提供免疫力,但我把之前的AB阳性测试当作可以挥手的盾牌,大喊:“我去过那里,去过那里,做过那件事,我没事。”对或错。现在我宝贵的保护消失了。Pzd世界播


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Pzd世界播

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I called the testing center. "Surely some mistake," I said grandly. "I have previous tests to prove it." The center, having not seen a case of a re-test losing antibodies before, went back to the lab to see what was going on. Pzd世界播

我给考试中心打了电话。“肯定是弄错了,”我庄严地说。“我有之前的测试可以证明这一点。”该中心之前没有见过重新检测丢失抗体的情况,于是回到实验室看看发生了什么。Pzd世界播


The lab responded, "Oh no, Mr. Quest does have antibodies, just not enough to register on the scale." I had registered as 1 on the 'scale,' and only those above 1.4 are considered to have enough antibodies to classify as positive. Pzd世界播

实验室回答说,“哦,不,奎斯先生确实有抗体,只是不足以在秤上登记。”我在“标尺”上登记为1,只有那些超过1.4的人才被认为有足够的抗体被归类为阳性。Pzd世界播


I needed to know more, so immediately launched into a whirlwind of googling, then battled through a scientific article on the Abbott SARS-CoV-2 IgG antibody test. IgG refers to immunoglobulin class G antibodies in your blood, which when washed, mixed and tumble-dried with other chemicals (as well as a load of other things I didn't understand), produces an antibody index, where the cut-off point is 1.4. And I had been cut off. Pzd世界播

我需要知道更多,所以立即开始了旋风式的谷歌搜索,然后奋力阅读了一篇关于雅培SARS-CoV-2IgG抗体测试的科学文章。IgG指的是你血液中的免疫球蛋白G类抗体,当它与其他化学物质(以及许多其他我不理解的东西)一起清洗、混合和滚筒干燥时,会产生一个抗体指数,截止点是1.4。我被切断了联系。Pzd世界播


Over the past five months my evanescent antibodies had dwindled to meaningless, and with it my bravado claim to protection. Now it seemed I was back to square one: vulnerable to Covid again. Pzd世界播

在过去的五个月里,我短暂的抗体已经变得毫无意义,随之而来的是我的虚张声势,声称自己受到了保护。现在,我似乎又回到了起点:再次易受科维德的攻击。Pzd世界播


When I told my infectious diseases doctor in New York, he wasn't one bit surprised. He referred to the latest studies showing that antibodies do indeed weaken and dwindle over 90 days -- no one has had a chance to do much research beyond that yet. Pzd世界播

当我告诉我在纽约的传染病医生时,他一点也不惊讶。他提到的最新研究表明,抗体确实会在90天内减弱和缩小--目前还没有人有机会在这之后做更多的研究。Pzd世界播


But, as my doctor continued, that's only half the body's defensive mechanism. T cells, an important part of our immune system's attack force, have virus memory. Pzd世界播

但是,正如我的医生继续说的那样,这只是身体防御机制的一半。T细胞是我们免疫系统攻击力的重要组成部分,具有病毒记忆力。Pzd世界播


They will lay quiescent until (or if) the body comes into contact with Covid-19 again, at which point my immune system will fire up and start producing antibodies once more. Pzd世界播

它们会静静地躺着,直到(或者如果)身体再次与新冠肺炎接触,那时我的免疫系统将会启动,并再次开始产生抗体。Pzd世界播


It was, my doctor said, "highly, highly unlikely that you will get Covid again this year ... medically improbable." I was then quickly admonished that none of this should lead me to abandon social distancing, hand washing and other anti-virus measures. Pzd世界播

我的医生说,“今年你再次感染Covid的可能性非常非常小……医学上不太可能。”然后,我很快被告诫说,所有这些都不应该导致我放弃社交距离、洗手和其他防病毒措施。Pzd世界播


Resilience, but no immunity? Pzd世界播

有韧性,却没有豁免权?Pzd世界播


I relate all of this because it's another example of our collective tortuous journey with this disease. The circuitous progress of the pandemic creates fear, then hope, then back to fear again, seemingly with no end. Pzd世界播

我之所以将这一切联系起来,是因为这是我们与这种疾病共同曲折之旅的又一个例子。大流行的曲折发展带来了恐惧,然后是希望,然后又回到了恐惧中,似乎没完没了。Pzd世界播


I have seen many Covid recoverees quietly parade their antibody status as if it is a shield for life. Yet I would bet good money that if they took another test they would also discover that their armor has cracked, or has holes in it. Pzd世界播

我见过许多Covid恢复者悄悄地炫耀他们的抗体状态,就像它是生命的盾牌一样。然而,我敢打赌,如果他们再做一次测试,他们也会发现他们的盔甲已经破裂,或者有洞。Pzd世界播


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What happened on Richard Quest's first flight in four months Pzd世界播

理查德·奎斯特四个月来的首次飞行发生了什么Pzd世界播


I only discovered the curious case of my dwindling antibodies because I get tested frequently because of my travels for work. Pzd世界播

我只是发现了我的抗体减少的奇怪情况,因为我经常因为出差而接受检测。Pzd世界播


I like to think common sense tells me that I can't catch Covid again in the short term -- otherwise we would have heard of many more cases of re-infection. So far there have only been a few outlier cases and they tend to have unique circumstances. Yet common sense must now be trumped by that hoary but voguish cliché: the "abundance of caution." I will only take common sense so far. Pzd世界播

我认为常识告诉我,我在短期内不可能再次感染Covid--否则我们会听说更多的再次感染病例。到目前为止,只有几个离群索居的案例,而且它们往往有独特的情况。然而,常识现在必须被那句陈词滥调所压倒:“高度谨慎”。到目前为止,我只接受常识。Pzd世界播


This is all teaching me that what was fact yesterday, doesn't mean it's the same today. Experts are saying we know a lot more about Covid now than we did six months ago. That is true at the helicopter level, where governments make national policies, and also at the grass roots, as I go about my life. Pzd世界播

这一切都在告诉我,昨天的事实并不意味着今天的情况是一样的。专家表示,与六个月前相比,我们现在对Covid的了解要多得多。这在直升机层面是正确的,在那里政府制定国家政策,也是在基层,当我开始我的生活时也是如此。Pzd世界播


My new reality is that I no longer have the antibodies of which I was once so proud. I may have a resilience based on T-cell memory and I am unlikely to be infected again, but I may! I just wonder what other "certainty" is going to crumble into the dust next. Pzd世界播

我的新现实是,我不再拥有我曾经引以为豪的抗体。我可能有一种基于T细胞记忆的弹性,我不太可能再次被感染,但我可能会!我只是想知道接下来还有什么“确定性”会化为乌有。Pzd世界播


While I wait to find out, I will follow the rules. Pzd世界播

在我等着找出答案的同时,我会遵守规则的。Pzd世界播

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