礼来公司出于安全考虑暂停抗体药物试验,特朗普将其吹捧为新冠肺炎的“治愈”

2020-10-14 12:03

Eli Lilly pauses trial of antibody drug Trump touted as COVID-19 'cure' over safety concern X2u世界播

礼来公司出于安全考虑暂停抗体药物试验,特朗普将其吹捧为新冠肺炎的“治愈”X2u世界播


(Reuters) - Eli Lilly and Co said on Tuesday that the government-sponsored clinical trial of its COVID-19 antibody treatment similar to one taken by U.S. President Donald Trump has been paused because of a safety concern. X2u世界播

(路透社)-礼来公司周二表示,出于安全考虑,其新冠肺炎抗体治疗的政府赞助的临床试验已暂停,该试验类似于美国总统唐纳德·特朗普的治疗。X2u世界播


Trump touted the Lilly drug, along with the antibody treatment from Regeneron Pharmaceuticals Inc that he received for his COVID-19, as tantamount to a cure in a video he posted last week. X2u世界播

特朗普在上周发布的一段视频中吹捧礼来公司的药物,以及他为他的新冠肺炎接受的Regeneron制药公司的抗体治疗,相当于一种治愈方法。X2u世界播


The announcement comes one day after Johnson & Johnson said it was forced to pause a large high-profile trial of its experimental coronavirus vaccine because a volunteer fell ill. J&J said it does not yet know if that person was given the vaccine or a placebo. X2u世界播

此前一天,强生公司表示,由于一名志愿者生病,该公司被迫暂停其实验性冠状病毒疫苗的一项大型高调试验。强生表示,目前还不知道这名患者是接种了疫苗还是服用了安慰剂。X2u世界播


AstraZeneca Plc's U.S. trial for its experimental COVID-19 vaccine has also been on hold for over a month after a volunteer in its UK study fell ill. Trials of that vaccine resumed in other regions after a brief halt. X2u世界播

阿斯利康(AstraZeneca Plc)在美国对其实验性新冠肺炎疫苗的试验也已经暂停了一个多月,因为其英国研究中的一名志愿者生病了。在短暂暂停后,该疫苗在其他地区的试验重新开始。X2u世界播


Lilly said earlier this month it was applying for emergency use authorization (EUA) for the antibody drug, LY-CoV555, for patients with mild to moderate COVID-19 based on data from another clinical trial. X2u世界播

礼来公司本月早些时候表示,它正在根据另一项临床试验的数据,为新冠肺炎轻中度患者申请抗体药物LY-CoV555的紧急使用授权。X2u世界播


It is not uncommon to pause drug trials to investigate safety concerns, and such actions do not necessarily indicate a serious problem. Because of the urgent need for drugs and vaccines to tackle a pandemic that has claimed over 1 million lives worldwide - and the speed with which they are being developed - these trials have come under intense scrutiny. X2u世界播

暂停药物试验以调查安全问题并不少见,这样的行为并不一定表明存在严重问题。由于迫切需要药物和疫苗来应对已在全球夺走100多万人生命的大流行-以及它们的开发速度-这些试验受到了严格的审查。X2u世界播


"Out of an abundance of caution, the ACTIV-3 independent data safety monitoring board (DSMB) has recommended a pause in enrollment," Lilly spokeswoman Molly McCully said in an emailed statement. "Lilly is supportive of the decision by the independent DSMB to cautiously ensure the safety of the patients participating in this study." X2u世界播

礼来公司发言人莫莉·麦卡利(Molly McCully)在一份电子邮件声明中表示:“出于高度谨慎,Acv-3独立数据安全监测委员会(DSMB)建议暂停注册。”礼来公司支持独立的DSMB谨慎确保参与这项研究的患者安全的决定。“。X2u世界播


The Indianapolis-based drugmaker did not comment on the implications for the paused trial, called ACTIV-3, which is testing the treatment on COVID-19 patients who require hospitalization, or on its other ongoing trials. It is also testing the drug in nursing homes to see if it can prevent staff and residents from getting infected. X2u世界播

这家总部位于印第安纳波利斯的制药商没有就暂停的名为ACTV-3的试验或其他正在进行的试验的影响发表评论。ACTV-3正在需要住院的新冠肺炎患者身上测试治疗。该公司还在疗养院测试这种药物,看看它是否可以防止工作人员和居民感染。X2u世界播


The U.S. Food and Drug Administration and the National Institutes of Health did not immediately reply to requests for comment. X2u世界播

美国食品和药物管理局(FDA)和美国国立卫生研究院(National Institutes Of Health)没有立即回复记者的置评请求。X2u世界播


Lilly began its ACTIV-3 trial in August and is aiming to recruit 10,000 patients primarily in the United States. X2u世界播

礼来公司于8月份开始进行Activ-3试验,目标是主要在美国招募1万名患者。X2u世界播


The trial compares patients who receive its antibody drug plus Gilead Sciences Inc's antiviral drug remdesivir with those who receive remdesivir alone. X2u世界播

这项试验比较了接受其抗体药物加Gilead Sciences Inc的抗病毒药物redesivir的患者和那些单独接受redesivir的患者。X2u世界播


Lilly sought the EUA from U.S. regulators after publishing data in September showing LY-CoV555 helped cut hospitalization and emergency room visits for COVID-19 patients. The treatment is being developed with Canadian biotech AbCellera. X2u世界播

礼来公司在9月份公布的数据显示,LY-CoV555有助于减少新冠肺炎患者的住院和急诊室就诊后,寻求美国监管机构的欧盟批准。这种疗法正在与加拿大生物技术AbCellera合作开发。X2u世界播


Lilly shares closed nearly 3%. X2u世界播

礼来公司股价收盘接近3%。X2u世界播

© 2016 世界播 www.shijiebobao.com 中国互联网举报中心 京ICP证140141号 鄂ICP备18018000号-1
违法和不良信息举报: