辉瑞将开始在12岁的儿童中测试新冠肺炎疫苗

2020-10-14 09:30

Pfizer to start testing its Covid-19 vaccine in children as young as 12 eRI世界播

辉瑞将开始在12岁的儿童中测试新冠肺炎疫苗eRI世界播


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Vaccine trial paused as Covid-19 cases surge in US eRI世界播

美国新冠肺炎病例激增,疫苗试验暂停eRI世界播


Drugmaker Pfizer has plans to start testing its experimental coronavirus vaccine in children as young as 12, and parents have already expressed interest in enrolling their kids, the researcher leading the trial told CNN Tuesday. eRI世界播

周二,领导这项试验的研究人员告诉CNN,制药商辉瑞(Pfizer)计划开始在12岁的儿童身上测试其实验性冠状病毒疫苗,父母已经表示有兴趣让他们的孩子报名。eRI世界播


It will be the first coronavirus vaccine trial to include children in the United States. eRI世界播

这将是美国第一次有儿童参加的冠状病毒疫苗试验。eRI世界播


A team at Cincinnati Children's Hospital will begin vaccinating teenagers aged 16 and 17 this week, and will move to enroll 12-to 15-year-olds later, said Dr. Robert Frenck, director of the Vaccine Research Center at the hospital. eRI世界播

辛辛那提儿童医院(Cincinnati Children‘s Hospital)疫苗研究中心主任罗伯特·弗兰克(Robert Frenck)博士表示,辛辛那提儿童医院的一个团队本周将开始为16岁和17岁的青少年接种疫苗,并将在晚些时候开始招收12至15岁的青少年。eRI世界播


The company confirmed on its website it has approval from the US Food and Drug Administration to enroll children as young as 12 in its trial. eRI世界播

该公司在其网站上证实,它已获得美国食品和药物管理局(US Food And Drug Administration)的批准,可以招募年仅12岁的儿童参加试验。eRI世界播


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"We really think a vaccine for adolescents and children is going to be critical for getting Covid under control," Frenck told CNN in a telephone interview. eRI世界播

“我们真的认为针对青少年和儿童的疫苗对于控制Covid至关重要,”Frenck在一次电话采访中告诉CNN。eRI世界播


"I think one of the things that is important to remember is that although the death rate for children with Covid is lower than in older adults, it's not zero," he saId, noting that more than half a million children have been diagnosed with coronavirus in the US. "It is not a nonexistent infection in children." eRI世界播

他说:“我认为需要记住的重要一点是,尽管Covid患儿的死亡率低于老年人,但也不是零。”他指出,美国已有50多万儿童被诊断出感染了冠状病毒。“这在儿童中并不是一种不存在的感染。”eRI世界播


Children can develop serious illness and also die from coronavirus and there is no way to predict which ones will, he said. They also can spread it to other, more vulnerable people, including parents, grandparents, healthcare workers and others. And children can develop a rare but serious side-effect from coronavirus infection called multisystem inflammatory syndrome in children or MIS-C. eRI世界播

他说,儿童可能会患上严重的疾病,也可能死于冠状病毒,没有办法预测哪些会死。他们还可以将其传播给其他更脆弱的人,包括父母、祖父母、医护人员和其他人。儿童可能会因冠状病毒感染而出现一种罕见但严重的副作用,称为儿童多系统炎症综合征或MIS-C。eRI世界播


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Kids struggle with Covid-19 and its months of aftermath eRI世界播

孩子们与新冠肺炎及其数月的后果作斗争eRI世界播


Frenck also believes more children have been infected with coronavirus than the official data show. "I think we are probably under detecting the number of kids that are infected because they are not getting sick enough to where a parent says they need to go to a doctor," he said. eRI世界播

弗朗克还认为,感染冠状病毒的儿童比官方数据显示的要多。他说:“我认为我们可能没有检测到被感染的孩子的数量,因为他们的病情还没有达到父母说他们需要去看医生的地步。”eRI世界播


"Most of the time in kids, you have a young kid at home and they have a runny nose, they have a cough -- you are not going to bring them to a doctor," he added. eRI世界播

他补充说:“大多数情况下,孩子家里有个小孩,他们流鼻涕,咳嗽--你不会带他们去看医生。”eRI世界播


"And most of the time, what a coronavirus causes is a cold." eRI世界播

“在大多数情况下,冠状病毒导致的是感冒。”eRI世界播


Plus, the FDA has asked the companies working to make a coronavirus vaccine to test them in diverse groups -- including in people usually missed in drug and vaccine trials, such as the elderly, Blacks, Hispanics and Native Americans. eRI世界播

此外,FDA已经要求致力于制造冠状病毒疫苗的公司在不同的群体中进行测试-包括在药物和疫苗试验中通常错过的人,如老年人、黑人、西班牙裔和美洲原住民。eRI世界播


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New ads encourage minorities to roll up their sleeves and participate in coronavirus vaccine trials eRI世界播

新广告鼓励少数族裔撸起袖子参加冠状病毒疫苗试验eRI世界播


Pfizer, one of four companies to have vaccines in advanced, Phase 3 clinical trials in the US, says it has enrolled close to 38,000 volunteers in its trial. More than 31,000 of them have received the second of two shots. eRI世界播

辉瑞(Pfizer)是在美国进行高级3期临床试验的四家公司之一,该公司表示,它已经招募了近3.8万名志愿者参加试验。其中超过3.1万人已经接受了两针中的第二针。eRI世界播


Frenck said more than 90 people have responded to an ad looking for volunteers to sign up teens for the trial. eRI世界播

Frenck说,已经有90多人响应了一则寻找志愿者的广告,让青少年报名参加试验。eRI世界播


Pfizer developed its two-dose coronavirus vaccine with Germany's BioNtech. It uses pieces of viral genetic material to induce immunity to the coronavirus. eRI世界播

辉瑞公司与德国生物科技公司合作开发了两剂冠状病毒疫苗。它使用病毒遗传物质来诱导对冠状病毒的免疫力。eRI世界播


"If regulatory approval or authorization is obtained, the companies expect to manufacture globally up to 100 million doses by the end of 2020 and potentially 1.3 billion doses by the end of 2021," the company said on its website. eRI世界播

该公司在其网站上表示:“如果获得监管部门的批准或授权,预计到2020年底,这些公司将在全球生产多达1亿剂,到2021年底,可能生产13亿剂。”eRI世界播

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